Increased connectivity and open access to the Internet provide malicious actors with novel opportunities for intelligence gathering, attacks on vulnerable targets, and shaping mass perceptions and behavior. In the editorial article to this edition of Connections, the issue editors review recent and emerging security-related challenges and responses. The focus is on the increase in cybercrime, corruption, the spread of hate speech, propaganda, and disinformation. In addition, the contributors elaborate on prospective solutions such as strengthening the legal regimes, including international norms, instituting confidence-building measures, and enhancing cyber skills, as well as the challenges for defense posed by the advances in quantum computing.